MCAO相关论文
目的探究miR-153在脑缺血再灌注中的表达及相关作用机制。方法小鼠脑内注射miR-153 agomir进行过表达miR-153,采用短暂局灶性大脑......
研究背景和目的中风是世界上致死致残最高的疾病之一,分为缺血性和出血性中风,其中缺血性中风的比例超过80%。缺血性中风是脑动脉......
Paeoniflorin ameliorates ischemic injury in rat brain via inhibiting cytochrome c/caspase3/HDAC4 pat
Paeoniflorin(PF),a bioactive monoterpene glucoside,has shown a variety of pharmacological effects such as anti-inflammat......
脑血管病已经成为人类致死致残最主要的原因之一,其发病率有逐年上升的趋势,其中以缺血性脑卒中最常见。神经干细胞的发现和分离成......
目的探究TNF-α-NF-κB信号通路在大鼠脑缺血（Cerebral ischemia,CI）模型中的作用,并予以常压氧（Normobaric oxygen,NBO）治疗作为干预......
研究背景与目的:脉安肽是一种新型直接凝血酶抑制剂,我们前期研究已证实其抑制微型猪股动脉球囊损伤后新生内膜的形成,同时抑制血......
脑缺血后,常会出现出血转化的现象,这属于急性脑梗死后自然病程的一部分。其发生原因主要是由于溶栓治疗后血脑屏障结构（如内皮细胞......
背景:缺血性脑卒中后神经炎症主导脑损伤的病理过程,同时也是影响卒中预后的主要因素。长非编码RNA（lncRNA）在各种疾病中均发挥着调......
Salvianolic acid A (SAA) is a water-soluble component from the root of Salvia Miltiorrhiza Bge,a traditional Chinese med......
Purpose: To evaluate the effects of γ-secretase inhibitor treatment after transient cerebral ischemia using magnetic re......
Purpose: About 3.3 million deaths resulted from ischemic stroke. 1 Predicting tissue fate in ischemic stroke is of criti......
Ethnopharmacological relevance:Tongxinluo (TXL),a renowned traditional Chinese medicine,consistsof several different kin......
Angiotensin Ⅱ type Ⅰ receptor-mediated oxidative stress in rostral ventrolateral medulla underlies t
Stroke is a major health problem throughout the world.The elevated blood pressure (BP) after stroke is a common complica......
Oral administration of ampelopsin protects against acute brain injury in rats after focal cerebral i
Ampelopsin (AMP) isolated from the Chinese medicinal herb Ampelopsis grossedentata (Hand-Mazz) manifests numerous biolog......
目的：SIRT1是Ⅲ类组蛋白去乙酰化酶，参与了高压氧预处理(HBO-PC)对脑缺血动物模型急性期的神经保护作用。然而，其是否参与了HBO-PC在......
Two kinds of Rhizoma Chuanxiong volatile oil and its protective effect on rats with cerebral ischemi
Objective Compare constituents ofRhizoma Chuanxiong volatile oil extracted in two methods and study its protective effec......
Therapeutic neuroprotective effects of Ginkgolide B on cortex and basal ganglia in a rat model of tr
Cerebral ischemia and reperfusion is one of the leading causes for death and severe disabilities in the world and often ......
Neuropotective effect of HAMI3379,a selective cysteinyl leukotriene receptor 2 antagonist,on focal c
Objective Cysteinyl leukotrienes(CysLTs)induce inflammatory responses mediated by activating CysLT1 and CysLT2 receptor.......
After focal cerebral infarction,corticospinal tract from the cerebral cortex on the healthy side can re-cross the midlin......
目的 研究白细胞介素4(IL-4)对小鼠局灶性脑缺血再灌注损伤(MCAO/R)的保护作用和可能的机制.方法 动物水平采用小鼠大脑中动脉阻塞......
OBJECTIVE Complement component C3(C3),a key factor in the complement system,is heavily involved in various inflammation-......
High-frequency repetitive transcranial magnetic stimulation promotes neurogenesis, and reduces subac
Repetitive transcranial magnetic stimulation(rTMS)has rapidly become an attractive therapeutic approach for stroke.Howev......
Novel hydrogen sulfide releasing derivatives of 3-n-Butylphthallde attenuate ischemic brain damage i
Aim: NBP was employed as the lead compound to obtain a novel class of H2Sreleasing derivatives.We investigated their ant......
Physical exercise improves functional recovery through mitigation of autophagy, apoptosis and enhanc
Background It is well known that physical exercise is beneficial to functional recovery after stroke,but the mechanisms ......
High-frequency repetitive transcranial magnetic stimulation promotes neurogenesis, and reduces acute
Repetitive transcranial magnetic stimulation (rTMS) has rapidly become an attractive therapeutic approach for stroke.How......
Physical exercise regulates neural stem cells proliferation and migration via SDF-1α/CXCR4 pathway i
Physical exercise is beneficial to functional recovery after stroke.But its underling mechanism is still unknown.It is r......
目的 探讨CH03对于局灶性脑缺血模型(MCAO)大鼠产生的炎症因子的影响.方法 实验分为假手术组,模型组,低、中、高剂量CH03(1.5,3和6......
Preexisting Interleukin-10 In Susceptible Cerebral Arteries May Decrease Subsequent Brain Injury Cau
...
Proteomic analysis of focal cerebral ischemia/reperfusion injury in rats indicated changes of multip
Stroke is a leading cause of mortality and long-term disability and ischemic stroke accounts for 87%of all strokes....
目的 探讨川蛭通络胶囊对小鼠局灶性脑缺血再灌注损伤的保护作用.方法 采用ICR小鼠中动脉阻断(MCAO)制备小鼠局灶性脑缺血再灌注模......
目的:通过观察大脑中动脉闭塞(MCAO)大鼠血浆TAT、F1+2、D-二聚体、v WF含量的动态变化,探讨MCAO大鼠缺血后血栓生物标记物的变化......
目的:观察补阳还五汤对局灶性脑缺血损伤模型大鼠微循环血流及相关因子的影响。方法:实验分为假手术组,模型对照组,阿托伐他汀组(1......
Stroke persists as a global health and economic crisis, yet only two interventions to reduce stroke-induced brain injury......
目的：观察电针对MCAO 大鼠EphrinB2/EphB2 信号通路上突触重塑相关因子表达的影响,以期揭示针刺治疗脑缺血的可能机制。方法：120......
目的观察不同环境设置对局灶性脑梗死大鼠学习记忆能力及梗死灶周围胆碱乙酰转移酶(ChAT)表达的影响。方法将SD大鼠用电凝法造成右......
目的:研究滁菊总黄酮(TFCJ)抗大鼠局灶性脑缺血再灌注损伤(FCIRI)作用。方法:取120只雄性SD大鼠,随机分为6组,即假手术组、模型组......
背景及目的目前,治疗缺血性脑卒中后,大多数患者会遗留神经功能缺损,出现不同程度的功能活动丧失或残疾,如偏瘫、视物不清、失语、......
MTB-1806(5-bromo-2-(5-fluoro-1-hydroxyamyl)benzoate calcium,5-溴-2-(5-氟-1-羟戊基)苯甲酸钙)是在丁苯酞(3-n-butylphthalide......
近年来,人们发现嘌呤信号分子及其受体在神经发育及其生理功能中,发挥着重要作用,它们通过介导神经元和胶质细胞间的相互作用,参与......
第一部分经鼻给药tPA突变体改善小鼠缺血性脑卒中后长期神经损伤的作用目的:研究小鼠缺血性脑损伤(MCAO)模型中,术后给予多剂量tPA......
脑血管疾病是一种严重危害人类健康的常见病和多发病,尤其是缺血性脑血管病,具有很高的发病率、致残率和复发率。中药和天然药物中......
